Research guide

Mecasermin

Increlex · Recombinant IGF-1

A replacement form of IGF-1 used for a narrowly defined growth disorder.

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Product statusApproved
Development snapshotApproved

How it works, simply

It supplies a growth signal that is insufficient in the indicated population.

What the evidence tells us

It is not a general muscle-building medicine; the diagnostic criteria and risks are specific.

Watch with PEP 7

A short introduction; the sources and limitations remain important.

Open video guide

Video guides are coming soon.

Risks and open questions

  • Severe hypoglycemia is an important risk.
  • Intracranial hypertension and growth of lymphoid tissue are also described in the label.

Research and education only. PepGuide does not recommend medicines, doses or protocols.

Technical details and study context

Mechanism: Activates the IGF-1 receptor to support growth in a narrowly defined deficiency population.

Sponsor or developer: Ipsen

Studied or labeled topics: Severe primary IGF-1 deficiency

Commercial blend names and research vials do not inherit a medicine’s approval or manufacturing controls.

Sources and review dates

Product labels and further research

These directories help locate records. They are not individual studies supporting every statement.

Readability updated October 10, 2026. Evidence review: October 10, 2026 (linked label: purpose and selected risks). A wording update is not a new clinical review.