Research guide

Zenagamtide

Amycretin · NN9487

Zenagamtide, previously called amycretin, is studied for weight and metabolic outcomes.

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Product statusInvestigational
Development snapshotPhase 3 obesity program

How it works, simply

It combines amylin and GLP-1 signaling in one molecule.

What the evidence tells us

The newer name does not mean it is an approved product; formulation-specific trial results matter.

Watch with PEP 7

A short introduction; the sources and limitations remain important.

Open video guide

Video guides are coming soon.

Risks and open questions

This guide does not establish a safe dose, interaction profile or long-term safety for self-use. Effects reported for one route or formulation may not apply to another.

Research and education only. PepGuide does not recommend medicines, doses or protocols.

Technical details and study context

Mechanism: Combines amylin and GLP-1 receptor agonism in one investigational asset.

Sponsor or developer: Novo Nordisk

Studied or labeled topics: Obesity, Type 2 diabetes

2026-08-05: Sponsor update describes the Phase 3 AMAZE obesity program and planned diabetes development.

Commercial blend names and research vials do not inherit a medicine’s approval or manufacturing controls.

Sources and review dates

Readability updated October 10, 2026. Evidence review: September 23, 2026 (listed facts only). A wording update is not a new clinical review.